Polymethyl Methacrylate
Polymethyl methacrylate treats medium-to-deep wrinkles. Polymethyl methacrylate is PMMA. PMMA fillers contain about 20 percent of tiny PMMA microspheres in 80 percent purified collagen gel. A few months after injection, the collagen gel breaks down and the body produces its own natural collagen to fill out the space under the skin. This type of dermal filler, considered semi-permanent, treats medium-to-deep wrinkles, folds and furrows, and particularly nasolabial folds. It fills out pitted scars and augments thin lips. Patients choose PMMA instead of collagen replacement therapy or hyaluronic therapy because it offers a more permanent solution to facial wrinkles. Surgeons have used PMMA in permanent surgical implants for many years. One of the downsides of PMMA is that a number of injections needed to create the desired collagen volume can take up to three months. Sometimes PMMA is visible under the skin. To avoid any unwanted results, every plastic surgeon should be familiar with the proper technique, which involves PMMA injection at the dermal subcutaneous junction using threading or tunneling methods. PMMA, properly delivered, offers long-lasting results. The only FDA-approved brand of PMMA is Artefill.
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